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单位:成都大学新葡的京集团35222vip-Welcome、农业农村部杂粮加工重点实验室
通讯地址:成都市成洛大道2025号
电话:028-84616653
邮箱:renyuanhang@cdu.edu.cn
简介:
博士毕业于四川大学农药学专业。主要从事农药活性天然产物分子发掘与利用、农药毒理学等方向研究。近年来主持及参与各级科技计划项目十余项,先后在《Journal of Agricultural & Food Chemistry》、《Pest Management Science》、《Pesticide Biochemistry & Physiology》等领域内主流期刊上发表论文三十余篇,其中第一或通讯作者论文19篇。主讲研究生及本科生《蛋白质工程》,《有机化学实验》等课程。指导学生获国家及省级创新训练计划立项及学科竞赛奖多项。
主要科研项目:
1. 国家自然科学基金青年科学基金项目,靶向Kv介导下游信号途径的瑞香狼毒双黄酮抗虫机制研究(32102254),2022-2024年,主持
2. 四川省科技厅应用基础研究,基于钾离子通道阻断活性探究瑞香狼毒中双黄酮成分及其杀虫机理(2021YJ0477),2021-2023年,主持
3. 农业农村部重点实验室开放课题,苦荞中抗虫、抑菌活性组分筛选及作用机理研究(2019CC12),2019-2021年,主持
4. 四川大学研究生科研创新基金,瑞香狼毒中昆虫神经细胞毒性物质分离鉴定及作用机理研究(2018YJSY057),2018-2019年,主持
5. 国家重点研发计划项目课题,西北地区青稞、荞麦生产技术集成与示范区建设(2020YFD1001403),2020-2022年,主研
6. 四川省科技厅重点研发计划,西藏青稞、荞麦高值化复配产品研发及其专用品种筛选(22QYCX0077),2022-2023年,主研
7. 四川省科技厅科技扶贫项目,美姑县苦荞产业技术集成与科技扶贫示范基地建设(2021ZHFP0018),2021-2023年,主研
代表性论文:
1. Xuan He#, Lidan Lu#, Ping Huang, Bo Yu, Lianxin Peng, Liang Zou, Yuanhang Ren*. Insect cell-based models: cell line establishment and application in insecticide screening and toxicology research. Insects. 2023 (2): 104.
2. Yuanhang Ren, Xuan He, Yanting Yang, Yanan Cao, Qiang Li, Lidan Lu*, Lianxin Peng, Liang Zou. Mitochondria-mediated apoptosis and autophagy participate in buprofezin-induced toxic effects in non-target A549 cells. Toxics. 2022 (10): 551.
3. Yuanhang Ren, Xuan He, Xiyue Yan, Yanting Yang, Qiang Li, Tian Yao, Lidan Lu*, Lianxin Peng, Liang Zou. Unravelling the polytoxicology of chlorfenapyr on non-target HepG2 cells: the involvement of mitochondria-mediated programmed cell death and DNA damage. Molecules. 2022 (27): 5722.
4. Yuanhang Ren, Qiang Li, Lidan Lu, Hong Jin, Ke Tao*, Taiping Hou*. Isochamaejasmin induces toxic effects on Helicoverpa zea via DNA damage and mitochondria-associated apoptosis. Pest Management Science. 2021 (1): 557-567.
5. Yuanhang Ren, Qiang Li, Lidan Lu, Hong Jin, Ke Tao*, Taiping Hou*.Toxicity and physiological actions of biflavones on potassium current in insect neuronal cells. Pesticide Biochemistry & Physiology. 2021 (171):104735.
6. Yuanhang Ren, Hu Xia, Lidan Lu*, Gang Zhao. Characterization of the complete chloroplast genome of Hordeum vulgar L. var. trifurcatum with phylogenetic analysis. Mitochondrial DNA Part B Resources. 2021. 6 (7): 1852-1854.
7. Yuanhang Ren, Lidan Lu, Maoling Tan, Yanan Cao, Lianxin Peng*. Characterization of the complete mitochondrial genome of Meira sp. (Exobasidiales: Brachybasidiaceae) with phylogenetic analysis. Mitochondrial DNA Part B Resources. 2020 (3): 2607-2608.
8. Yuanhang Ren#, Jiaxing Shi#, Yangping Mu, Hong Jin*, Ke Tao, Taiping Hou. AW1 neuronal cell cytotoxicity: the mode of action of insecticidal fatty acids. Journal of Agricultural and Food Chemistry. 2019 (43): 12129-12136.
9. Yuanhang Ren, Yangping Mu, Ying Yue, Hong Jin, Ke Tao*, Taiping Hou*. Neochamaejasmin A extracted from Stellera chamaejasme L. induces apoptosis involved mitochondrial dysfunction and oxidative stress in Sf9 cells. Pesticide Biochemistry & Physiology. 2019 (43): 169-177.
10. Yuanhang Ren, Liqin He, Hong Jin*, Ke Tao*, Taiping Hou. Cytotoxicity evaluation and apoptosis-inducing effects of furanone analogs in insect cell line SL2. Food and Agricultural Immunology. 2018 (29): 964-975.
11. Yuanhang Ren, Na Yang, Ying Yue, Hong Jin, Ke Tao*, Taiping Hou. Investigation of novel pyrazole carboxamides as new apoptosis inducers on neuronal cells in Helicoverpa zea. Bioorganic & Medicinal Chemistry. 2018 (26): 2280-2286.
12. Yuanhang Ren, Hong Jin, Ke Tao*, Taiping Hou. Apoptotic effects of 1,5-bis-(5-nitro-2-furanyl)-1,4-pentadien-3-one on Drosophila SL2 cells. Molecular & Cellular Toxicology. 2015 (11): 187-192.