赵琦，1981年4月出生，博士，教授，硕士生导师，成都大学“川藏特色药用植物资源开发利用四川省高校工程研究中心”负责人。四川省杰出青年科技人才，四川省学术技术带头人后备人选，成都市龙泉驿区科协副会长，四川省植物学会理事，成都大学“1315”人才工程青年骨干教师，主持国家自然科学基金、四川省杰出青年科技人才项目、科技支撑项目等省部级以上课题10余项。以第一或通讯作者在Journal Of Hematology & Oncology、Journal of Ethnopharmacology、BMC Plant Biology、GCB Bioenergy、《中草药》、《分子植物育种》等国内外知名学术期刊发表论文40余篇。在科学出版社出版专著1部。授权发明专利3项。培养研究生20余名。
主要科研项目
国家自然科学基金面上项目，基于TRPV1通路的川贝母栽培品镇咳药效物质基础研究
国家自然科学基金青年项目，卷叶贝母再生鳞茎生物碱高效累积相关基因资源发掘与激素调控激励研究
四川省杰出科技人才项目，不同基源川贝母镇咳药效的物质基础研究
四川省省科技厅应用基础项目，西贝母碱与化疗药联用对人肺癌细胞耐药性的逆转效果研究
四川省科技厅科技支撑项目，川贝母组织培养中甾类生物碱累积的分子基础
四川省中医药管理局中药应用研究项目，藏药波棱瓜雌雄株早期性别鉴定研究技术开发与应用
成都市产业升级牵引工程-农业技术研发项目，卷叶贝母工厂化繁育技术研究与开发
代表论文
1. Jian Li#, Wenwen Li#, Kejiang Huang, Yang Zhang, Gary Kupfer, Qi Zhao*. Chimeric antigen receptor T cell (CAR-T) immunotherapy for solid tumors: lessons learned and strategies for moving forward. Journal of Hematology & Oncology, 2018,11(1):22. (IF=17.39)
2. Qi Zhao#, Rui Li, Yingying Gao, Xiaoqiang Guo, Wenguo Wang* Modeling impacts of climate change on the geographic distribution of medicinal plant Fritillaria cirrhosa D. Don. Plant Biosystems, 2018, 152(3), 349-355. (IF=2.83)
3. Qi Zhao#, Rui Li#, Yang Zhang, Kejia Huang, Wenguo Wang*, Jian Li* Transcriptome analysis reveals in vitro-cultured regeneration bulbs as a promising source for targeted Fritillaria cirrhosa steroidal alkaloid biosynthesis. 3 Biotech, 2018,8(4),191. (IF=2.41)
4. Yu Deng#*, Fulun Li#, Pinglin He, Yafei Yang, Jin Yang, Yamei Zhang Junying Liu, Yongping Tong, Qingfeng Li, Xian Mei, Zengyi Shu, Qi Zhao*. Triptolide sensitizes breast cancer cells to Doxorubicin through the DNA damage response inhibition. Molecular Carcinogenesis,2018,57(6):807-814. (IF=4.78)
5. WangWenguo#, Li Rui, Wang Hong, Qi Bufan, Jiang Xiaomei, Zhu Qili, Cai Denggao, Tang Xiaoyu, Zhao Qi*. Sweetcane (erianthus arundinaceus) as a native bioenergy crop with environmental remediation potential in southern china: a review. GCB Bioenergy,2019,11(9),1012-1025. (IF=4.75)
6. Rui Li, Yang Zhang, Yucheng Wang, Kejia Huang, Qianye Yang, Tiantian Zhang, Kun Xie, Jian Li, Qi Zhao*; Aqueous extract of Fritillariae cirrhosae induces cellular apoptosis through activation of STATs-mediated immunomodulation, Journal of Ethnopharmacology, 2020, 261. (IF=4.36)
7. Yixi Yang, Yujin Zhang, Xun Chen, Zhou Su, Yu Deng, Qi Zhao*; Khasianine ameliorates psoriasis-like skin inflammation and represses TNF-α/NF-κB axis mediated transactivation of IL-17A and IL-33 in keratinocytes, Journal of Ethnopharmacology, 2022, 292:115124. (IF=5.4)
8. Qiuxia Lu, Jiaqing Liao, Yuqin Hu, Yundong Gao, Mingcheng Wang, Jian Li, Qi Zhao*; Integrative analysis of the steroidal alkaloids distribution and biosynthesis of bulbs Fritillariae Cirrhosae through metabolome and transcriptome analyses, BMC Genomics, 2022, 23: 511. (IF=4.4)
9. Yixi Yang, Bowen Zhang, Ying Baom Peng Huang, Jian Li, Rui Li, Qi Zhao*; Chromosome-level genome assembly of Herpetospermum pedunculsum (Cucurbitaceae), Genome Biology and Evolution, 2023, 15(2): evad005. (IF=4.065)
10. Ya Zhong, Bowen Zhang, Jintao Li, Xin Zeng, Junxia Pei, Yamei Zhang, Yixi Yang, Fulun Li, Yu Deng, Qi Zhao*; Ethanol Extract of Herpetospermum caudigerum Wall ameliorates psoriasis-like skin inflammation and promotes degration of keratinocyte-derived ICAM-1 and CXCL9, Journal of Integrative Medicine, 2023, 305: 116069. (IF=3.951)
